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2 surprising jobs appear to protect against death from Alzheimer’s disease



Taxi and Ambulance Drivers: Unexpected Defenders Against Alzheimer's

A groundbreaking study from Mass General Brigham and Harvard Medical School has uncovered a surprising link between certain occupations and brain health. Researchers discovered that taxi and ambulance drivers may have a unique advantage in fighting Alzheimer's disease.

## The Key Findings

By analyzing nearly 9 million death certificates across 443 different occupations, the researchers found remarkable differences in Alzheimer's-related mortality:

- Overall population: 3.88% died from Alzheimer's

- Taxi drivers: Only 1.03% died from Alzheimer's

- Ambulance drivers: A remarkable 0.74% died from Alzheimer's

## Why These Professions Matter

The secret lies in spatial navigation. Unlike bus or airplane drivers who follow fixed routes, taxi and ambulance drivers constantly solve real-time navigation puzzles. This mental exercise appears to provide a powerful workout for the brain, particularly the hippocampus – a crucial region involved in both spatial memory and Alzheimer's progression.

## The Brain Science Behind the Discovery

Lead author Vishal Patel explains that the same brain area responsible for creating cognitive spatial maps is also linked to Alzheimer's development. Previous research has shown that London taxi drivers, who must memorize thousands of streets, actually develop larger hippocampi through their work.

## Important Nuances

The researchers are careful to note that this is an observational study and not a definitive conclusion. However, the findings suggest that complex mental activities challenging spatial thinking could potentially offer cognitive protection.

## Broader Implications

Senior author Anupam B. Jena emphasizes that the study is "hypothesis-generating." It raises intriguing questions about how mental engagement might defend against cognitive decline, offering hope that certain types of mental exercises could help protect brain health.

Take-Home Message

While not everyone can be a taxi or ambulance driver, the study suggests that engaging in mentally challenging activities that require active problem-solving and spatial navigation might be a powerful tool for maintaining cognitive resilience.

This research opens an exciting new avenue for understanding how our professional lives and mental activities could play a crucial role in brain health and Alzheimer's prevention.

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